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ADR Term
ADReCS ID
MedDRA Code
MeSH ID
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Drug ID
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ADR Ontology
ADR Term
Inflammation
ADR ID
BADD_A05823
ADR Hierarchy
08
General disorders and administration site conditions
08.01
General system disorders NEC
08.01.05
Inflammations
08.01.05.007
Inflammation
Description
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. [MeSH]
MedDRA Code
10061218
MeSH ID
D007249
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Not Available
Synonym
Inflammation localised | Inflammation localized | Inflammation NOS | Inflammatory reaction | Inflammatory swelling | Inflammation | Exudative inflammation | Inflammations
ADR Related Proteins
Protein Name
UniProt AC
TTD Target ID
Interleukin-1 alpha
P01583
T16340
Interleukin-10
P29456
Not Available
Interleukin-6
P05231
T32578
Interleukin-8
P10145
T22658
Nuclear receptor subfamily 4 group A member 3
Q92570
T93949
Retinol-binding protein 1
P09455
Not Available
Tumor necrosis factor
P01375
T20178
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D00864
Ezetimibe
-
-
BADD_D00879
Fentanyl
-
-
BADD_D00898
Finasteride
0.001069%
BADD_D00931
Fluorouracil
0.004234%
BADD_D00932
Fluoxetine
-
-
BADD_D00945
Fluticasone
-
-
BADD_D00948
Fluvastatin
0.003736%
BADD_D00952
Folic acid
0.000588%
BADD_D00958
Formoterol
-
-
BADD_D00961
Fosamprenavir calcium
-
-
BADD_D00978
Fulvestrant
0.002206%
BADD_D00979
Furosemide
-
-
BADD_D00980
Fusidic acid
-
-
BADD_D00981
Gabapentin
-
-
BADD_D00983
Gadobenate dimeglumine
-
-
BADD_D00989
Gadolinium
-
-
BADD_D01009
Gemcitabine
0.001332%
BADD_D01060
Heparin
-
-
BADD_D01073
Histrelin
-
-
BADD_D01086
Hydrocortisone
0.000335%
BADD_D01096
Hydromorphone
0.000826%
BADD_D01103
Hydroxychloroquine
0.000405%
BADD_D01117
Ibandronic acid
-
-
BADD_D01119
Ibrutinib
0.009857%
BADD_D01120
Ibuprofen
0.000056%
BADD_D01124
Icodextrin
-
-
BADD_D01133
Ifosfamide
-
-
BADD_D01135
Iloprost
0.001113%
BADD_D01136
Imatinib
-
-
BADD_D01142
Imiquimod
0.012745%
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